VitroScreen - A SenzaGen Group company

Testing Facility and Headquarter
via Mosè Bianchi, 103
20149 Milano - Italy

25 years’ experience
on 3D advanced systems

In Vitro testing solutions

Delivering cutting-edge in vitro solutions with 3d human tissue expertise

We design and execute rigorous preclinical in vitro studies, combining validated testing standards with fully customized protocols to deliver reproducible, decision-ready results. Our expertise covers multiple product categories and therapeutic areas, providing highly predictive platforms for both regulatory and efficacy assessment.

Our Certificates

European commission EU-Netval certificate

Italian Ministry of Health GLP Certificate

UNI EN ISO 9001:2015

UNI CEI EN ISO 13485:2021

European commission EU-Netval certificate

Italian Ministry of Health GLP Certificate

UNI EN ISO 9001:2015

UNI CEI EN ISO 13485:2021

European commission EU-Netval certificate

Italian Ministry of Health GLP Certificate

UNI EN ISO 9001:2015

UNI CEI EN ISO 13485:2021

European commission EU-Netval certificate

Italian Ministry of Health GLP Certificate

UNI EN ISO 9001:2015

UNI CEI EN ISO 13485:2021

European commission EU-Netval certificate

Italian Ministry of Health GLP Certificate

UNI EN ISO 9001:2015

UNI CEI EN ISO 13485:2021

European commission EU-Netval certificate

Italian Ministry of Health GLP Certificate

UNI EN ISO 9001:2015

UNI CEI EN ISO 13485:2021

European commission EU-Netval certificate

Italian Ministry of Health GLP Certificate

UNI EN ISO 9001:2015

UNI CEI EN ISO 13485:2021

European commission EU-Netval certificate

Italian Ministry of Health GLP Certificate

UNI EN ISO 9001:2015

UNI CEI EN ISO 13485:2021

European commission EU-Netval certificate

Italian Ministry of Health GLP Certificate

UNI EN ISO 9001:2015

UNI CEI EN ISO 13485:2021

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Acne model: C.acnes

Assessing the efficacy of products in reducing and counteracting C.acnes invasion, growth and inflammation state on reconstructed skin models.

Adipogenesis and lipolysis

VitroScreenOra^®

Anti-aging

Anti-aging

VitroScreenOra^®

Anti-inflammatory

Antimicrobial adhesion

Atopic Dermatitis

Biofilm by crystal violet assay

Chronic fibrosis in corneal disease

VitroScreenOra^®

Cilia ultrastructure (SEM analysis)

Customized infected tissue models

Dandruff Model: Malassezia

Decongestant efficacy

Definition of MIC

Diabetic ulcer

Differential cartilage regeneration under stress and pro-inflammatory conditions.

VitroScreenOra^®

Dry eye disease: mild model and severe model

ECM boosting and remodeling

VitroScreenOra^®

ECM formation, assembly and remodeling

VitroScreenOra^®

Epithelial absorption and penetration according to OECD 428

Film Forming and Film Persistency

GARD® Air

Gastroesophageal reflux disease (GERD)

Hair cycling, anti-hair loss and hair growth efficacy

VitroScreenOra^®

Immuno-Competent Models (co-culture with THP1 Monocytes)

Immuno-modulatory activity

Inflammation

VitroScreenOra^®

Injectable MD-substance based efficacy

VitroScreenOra^®

Injectable MD-substance based efficacy

VitroScreenOra^®

Intestinal dysbiosis: E.coli

Irritation testing for medical devices (ISO 10993-23)

Irritation testing (OECD 439)

Metabolic competence: Cytochrome P450 activation/induction

VitroScreenOra^®

Metabolic disorders simulation after long-term exposure and lipid accumulation

VitroScreenOra^®

Microbiome safe

Microdilution Assays

Moisturizing efficacy

Inflammatory Bowel Disease (IBD) and chronic intestinal disorders.

VitroScreenOra^®

Onycomycosyis model: T.rubrum

Oral Dysbiosis: S.mutans

Osmolarity stress

Oxidative stress

Percutaneous absorption testing (OECD 428)

Percutaneous absorption testing (OECD 428)

Photo-damage

VitroScreenOra^®

Pro-inflammatory damages

VitroScreenOra^®

Protection against Exposome (particulate matter, Uvs, pollens, blue light)

Protective action against stress conditions

VitroScreenOra^®

Psoriasis

Senescence

Skin corrosion testing (OECD 431)

Skin Dryness

Skin sensitization, Epi2SensA

Skin sensitization, EpiSensA (OECD 442D, Appendix IC)

Skin sensitization, GARD® Skin Dose Response

Skin sensitization, GARD® Skin Medical Device

Skin sensitization, GARD® Skin (OECD442E)

Skin sensitization, KeratinoSens™ (OECD 442D, Appendix IA)

Striae distensa

Systemic exposure to postbiotics secretoms

VitroScreenOra^®

UVA and/or UVB stress - Photoprotection

UV activation and melanogenesis modulation: pigmentation and depigmentation (whitening test)

Vaginal dryness/atrophy

Vaginal Dysbiosis: C.albicans or G.vaginalis

Vasculogenesis and Angiogenesis

VitroScreenOra^®

Wound healing and re-epithelization

Wound healing on colonized skin