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25 years’ experience

on 3D advanced

systems

25 years’ experience

on 3D advanced

systems

25 years’ experience

on 3D advanced

systems

Non Clinical Models

Physiological and disease models on 3D Human Tissues dedicated to specific therapeutic areas and applicable to Cosmetics, Pharmaceuticals, Nutritionals, Medical Devices and Chemicals.

Non Clinical Models

Physiological and disease models on 3D Human Tissues dedicated to specific therapeutic areas and applicable to Cosmetics, Pharmaceuticals, Nutritionals, Medical Devices and Chemicals.

Microbiome Research Unit

Microbiome Research Unit

Microbiome Research Unit
Living bacteria on viable 3D tissues allow a deeper comprehension of the interactions between host and bacterium.

Microbiological Screening

  • Definition of MBC
  • Definition of MIC
  • Biofilm by crystal violet plate method
  • Interference on bacterial growth and metabolism
  • In vitro “sniff test”
  • Customized Microdilution Assays

Colonized 3D Human Reconstructed Tissues

  • Bacterial Adhesion: boosting or inhibiting bacterial growth and proliferative capacity
  • Anti-bacterial Efficacy
  • Anti-mycotic Efficacy: skin and nails
  • Bacterial and Yeasts competition models: skin, scalp, mucosae
  • Microbiome impact on barrier function: development, innate immunity, specific pathways modification
  • X-biotics MoA and Efficacy: pathogens inhibition and recognition
  • Wound healing on infected tissues
  • Microbiome safe claim
  • Anti-Fermentative, Anti-Cavity and Anti-Biofilm Formation on Gingival Mucosa
  • Healthy site specific microbiome model

Disease Model

  • Atopic Dermatitis: S. aureus
  • Acne lesions: C. acnes
  • Scalp microbiota: Dandruff Model
  • Biofilm models: anti-biofilm formation efficacy, influencing of EPS matrix production, biofilm disruption after acute or repeated treatments
  • Microbiome role in aging and pigmentation
  • Customized infected tissue models
  • Infected wounds healing
Microbiological Screening
  • Definition of MBC
  • Definition of MIC
  • Biofilm by crystal violet plate method
  • Interference on bacterial growth and metabolism
  • In vitro “sniff test”
  • Customized Microdilution Assays

Colonized 3D Human Reconstructed Tissues

  • Bacterial Adhesion: boosting or inhibiting bacterial growth and proliferative capacity
  • Anti-bacterial Efficacy
  • Anti-mycotic Efficacy: skin and nails
  • Bacterial and Yeasts competition models: skin, scalp, mucosae
  • Microbiome impact on barrier function: development, innate immunity, specific pathways modification
  • X-biotics MoA and Efficacy: pathogens inhibition and recognition
  • Wound healing on infected tissues
  • Microbiome safe claim
  • Anti-Fermentative, Anti-Cavity and Anti-Biofilm Formation on Gingival Mucosa
  • Healthy site specific microbiome model

Disease Model

  • Atopic Dermatitis: S. Aureus
  • Acne lesions: C. Acnes
  • Scalp microbiota: Dandruff Model
  • Biofilm models: anti-biofilm formation efficacy, influencing of EPS matrix production, biofilm disruption after acute or repeated treatments
  • Microbiome role in aging and pigmentation
  • Customized infected tissue models
  • Infected wounds healing