Within MEA approach (Multiple Endpoint Analysis) on 3D human reconstructed tissues and scaffold free spheroids, the morphological analysis and biomarkers localization and quantification are fundamental reads out. We are continuously strengthening our histological platform through additional capabilities and know-how: we perform standard and customized stainings, immunohistochemistry (IHC/IF) on 3D tissue models, skin explants and scaffold free spheroids both on paraffin blocks and on whole mount samples.